Spigelia Marilandica spig-m.

Spigelia Marilandica. Pink-root. Worm-grass. N. O. Loganiaceæ. Tincture of root.

Mania. Strabismus (r.).

The symptoms of Spi. m . are mainly from overdosing. A state of mania was induced in a boy from large and frequent doses of a decoction of the root. Strabismus of right eye was noted in one case.

Suddenly affected with complete mental derangement, exactly like that of Stram ., countenance distorted, running and skipping, fits of laughing and crying, pupils greatly dilated, talk wild and incoherent, (lasted 24h.).

Vertigo.

Wild, staring, ludicrous expression. — Irregular movement of adductors and abductors of eyes. — Strabismus of r. eye. — Pain in and about the eyes. — Sensation of stiffness of eyelids. — Pupils dilated.

Much swelling of face and about eyes. — Face flushed.

Tongue pointed and tremulous.

Pulse: accelerated; irregular.

On attempting to assume erect position, seized with general tremor lasting a few seconds and leaving her exhausted.

Drowsiness.

Skin hot and dry.

Spasmodic pains in the limbs, especially the joints.

Heaviness and soreness of the whole body.

Painful sensitiveness of the whole body to contact, with shivering of those parts that have been touched, or with formication through the whole body.

Marked aggravation of the symptoms after sexual excitability.

Stinging, tearing pains in association with twitchings of the affected areas.

Tearing near the joints, as from the scraping of a knife.

Masked intermittents, appearing as periodical face and headaches.

Aggravation when stooping and moving.

Heart disease, when the same are characteristized by violent and visible and audible palpitations.

Working, twitching or spasmodic movements of the eye-lids very marked when the remedy is indicated.

Disposition to squint.

Stitch or darting-like pain in the heart.