Angustura Vera ang.

Very much fatigued, feels it most in the thighs.

Caries and very painful ulcers, which affect the bones and pierce them to the marrow, particularly if the patient has longing for coffee and a very touchy, sensitive mind; very susceptible, will not bear the slightest joke (Ign.).

Timid; dyspeptic.

Traumatic tetanus (Hyper.).

From touching the affected part; 3 P. M., in afternoon.

Periodicity not marked.

3 P. M.—(Apis, Ars., Chin. s.)

Fevers occurring in tropical countries; after travelling through swamps in a hot climate (Ced.).

Violent chill every afternoon at 3 P. M. (Apis). Shivering with goose-flesh, without thirst, for several days in succession. Severe cold sensation over back; cold hands, fingers and feet; drawing pain in elbows, knees and toes (pains in ankles and wrists, Pod.). Chill lasts half an hour. Creepings up the back, with restlessness extending to inner parts, causing trembling with warm lips without thirst. Coldness, followed by heat the same day; recurring now in the evening, then at noon, then in the morning, with thirst in the beginning of the fever, and vomiting of bile.

Warmth of the whole body, except head, towards evening, so that she is unable to sleep again after 3 A. M. (worse at 3 A. M. and 3 P. M., Thuja). Cold cheeks. The heat ascends (Sep.). Flushes of heat with anxiety.

Perspiration at night in bed. Sweat only in the morning; on the forehead.

This remedy, like Cedron, is adapted to fevers of tropical climates. The paroxysm in each occurs at 3 P. M. (Apis), and is severe and prostrating.